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MedChemExpress
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Selleck Chemicals
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Santa Cruz Biotechnology
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ApexBio
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AK Scientific
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Enzo Biochem
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Air Products and Chemicals
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Tsang MD Inc
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MedChemExpress
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Altamira Inc
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Hiden Analytical
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Image Search Results
Journal: Genes & diseases
Article Title: PRMT1 promotes the proliferation and metastasis of gastric cancer cells by recruiting MLXIP for the transcriptional activation of the β-catenin pathway.
doi: 10.1016/j.gendis.2023.02.006
Figure Lengend Snippet: Figure 2 Cell proliferation and tumor growth were inhibited after PRMT1 expression was inhibited. (A) The expression of PRMT1 was examined through Western blot assays performed after PRMT1 expression was knocked down in HGC-27 and MKN-45 cells. Short hairpin (sh) GFP was used as the negative control, and tubulin was used as the loading control. (BeD) The proliferation rate of control and PRMT1-silenced cells was measured by MTT assay (B) after dimethyl sulfoxide (DMSO) and AMI-1 (a PRMT1 inhibitor)
Article Snippet: Two PRMT1 inhibitors,
Techniques: Expressing, Western Blot, Negative Control, Control, MTT Assay
Journal: Genes & diseases
Article Title: PRMT1 promotes the proliferation and metastasis of gastric cancer cells by recruiting MLXIP for the transcriptional activation of the β-catenin pathway.
doi: 10.1016/j.gendis.2023.02.006
Figure Lengend Snippet: Figure 3 PRMT1 promotes cell migration and invasion in vitro and in vivo. (AeD) Wound healing assays were performed after PRMT1 expression was knocked down in HGC-27 cells (A) and MKN-45 cells (B) and after cells were treated with AMI-1 and DCLX069 (C, D, respectively). (EeH) Transwell assays were performed with PRMT1 expression down-regulated in GC cells (E, F) treated with PRMT1 inhibitors (G, H), to measure cell migration and invasion in vitro. (I, J) GC cells with stably expressing PRMT1 knockdown vector or control cells were injected into nude mice via the tail vein. After one month, lung tissues were removed and stained with hematoxylin and eosin. Scale bar Z 2 mm.
Article Snippet: Two PRMT1 inhibitors,
Techniques: Migration, In Vitro, In Vivo, Expressing, Stable Transfection, Knockdown, Plasmid Preparation, Control, Injection, Staining